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Common names: U-47700
Systematic name: trans-3,4-dichloro-N-(2-(dimethylamino)cyclohexyl)-N-methylbenzamide
Psychoactive class: Opioid
Chemical class: Benzamide

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U-47700 is member of the drug class opioid analgesics. Specifically U47700 belongs to the benzamide class of opioids. It is not used medically but within scientific research. U-47700 is a research chemical mainly for the labs.

U-47700 has the systematic and formal IUPAC name 3,4-Dichloro-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]-N-methylbenzamide. It has a molar mass of 329.XXVII Hans C. J. Gram and an empirical chemical formula of C16H22Cl2N2O.

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It was first developed by a squad of researchers at the pharmaceutical firm Upjohn in the late 1970s.

In animal models U47700 was shown to have potency 7.5 times higher than the classical medicinal opiate morphine.

Pharmacologically U47700 is a selective agonist at the µ-opioid sense organ with a Kd of 5.3 nM in demarcation to a much weaker binding interaction at the kappa opioid receptor where U47700 have a Kd value of 910nM.

U47700 is a structural analogue of the early opioid AH-7921.

This compound is not fit for human or animal consumption.

Online reports whilst subjective and unverifiable do point to a number of qualities of this chemical.

U47700 is reported to produce feelings of euphoria, pain relief and curtailment of anxiety. Some users have reported issues comparable to the widely abused pharmaceutical oxycodone.

Euphoria is reported as less intense in comparison to morphine or heroin. The sensation produced is described as feeling of “warmth” and “comfort” which passes through the body.

U47700 is reported as causing significantly greater sedation than comparable opiate like oxycodone or hydrocodone. Other outcome include a reduction in libido, constriction of the pupils, trouble urinating, curtailment of cough and constipation. This is in keeping with the general side effects of opiates.

U47700 can induce itching of the skin due to release of histamine. Respiratory depression is a serious side effect of many opioids and is responsible for the lethality of these compounds.

Despite there being no formal studies in to the physiological action of U47700 in humans anecdotal report point to a propensity of U47700 to produce much stronger respiratory depression than heroin or morphine. This makes U47700 a dangerous compound and users need to access with extreme carefulness. At low does, it is reported that U47700 slows the breath moderately but will not produce a very noticeable impairment. Higher doses and overdoses overpower the user with abnormal breathing patterns reported, shortness of breath and loss of cognisance. This can quickly lead to fatal brain damage. U47700 like other opioids does produce a number of undesirable after effects that are colloquially known as the “crash”. These include excitement, irritability, negative emotional states, cognitive fatigue, difficulty thinking, anxiety, depression and lack of motivation. U47700 has a marked toxicity relative to dose due to its extreme potency in comparison to traditional opioids and opiates. This makes it a less than ideal recreational compound with significant risk of harm to the user. Therefore caution should be exercised with respect to dose. Deadliness of the compound is also exacerbated by concurrent use of other sedatives such as alcohol, benzodiazipines, Gamma hydroxybutyrate /GBL and dissociatives such as ketamine.

Properties of U-47700

Density:

1.2±0.1 g/cm3

Boiling Point:

464.8±45.0 °C at 760 mmHg

Vapour Pressure:

0.0±1.1 mmHg at 25°C

Enthalpy of Vaporization:

72.6±3.0 kJ/mol

Flash Point:

234.9±28.7 °C

Index of Refraction:

1.573

Molar Refractivity:

88.5±0.4 cm3

#H bond acceptors:

3

#H bond donors:

0

#Freely Rotating Bonds:

3

#Rule of 5 Violations:

0

ACD/LogP:

3.14

ACD/LogD (pH 5.5):

0.62

ACD/BCF (pH 5.5):

1.00

ACD/KOC (pH 5.5):

2.09

ACD/LogD (pH 7.4):

1.52

ACD/BCF (pH 7.4):

2.53

ACD/KOC (pH 7.4):

16.39

Polar Surface Area:

24 Å2

Polarizability:

35.1±0.5 10-24cm3

Surface Tension:

47.0±5.0 dyne/cm

Molar Volume:

268.5±5.0 cm3

Names & Synonyms of U-47700

3,4-Dichlor-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]-N-methylbenzamid [German][ACD/IUPAC Name]

3,4-Dichloro-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]-N-methylbenzamide[ACD/IUPAC Name]

3,4-Dichloro-N-[(1R,2R)-2-(diméthylamino)cyclohexyl]-N-méthylbenzamide [French][ACD/IUPAC Name]

Benzamide, 3,4-dichloro-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]-N-methyl-[ACD/Index Name]

3,4-Dichloro-N-(2-dimethylamino-cyclohexyl)-N-methyl-benzamide

 

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                Buy U-47700 powder online

                Buy U-47700 powder online

                Common names: U-47700
                Systematic name: trans-3,4-dichloro-N-(2-(dimethylamino)cyclohexyl)-N-methylbenzamide
                Psychoactive class: Opioid
                Chemical class: Benzamide

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